Actilyse alteplase How does it work?Actilyse injection contains the active ingredient alteplase, which is a type of medicine called a tissue type plasminogen activator, or fibrinolytic.
It is used to dissolve abnormal blood clots that have caused a heart attack, stroke or blood clot in the lung (pulmonary embolism). Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. Sometimes, however, a blood clot can form abnormally within the blood vessels. The clot can then get lodged in a blood vessel, blocking the blood supply to a vital organ such as the heart shop oakley sunglasses (causing a heart attack), brain (causing an ischaemic stroke) or lungs (causing a pulmonary embolism). ADVERTISEMENT oakley wallet CONTINUE READING BELOW Blood clots are made of red blood cells and platelets bound together with a substance called fibrin. Once they have fulfilled okay sunglasses their normal purpose of stopping bleeding, the body dissolves clots by producing another substance called plasmin. Plasmin breaks down fibrin and allows the clots to break up. Alteplase works oakley sunglasses store near me by attaching to the fibrin in abnormal blood clots, such as those in the arteries supplying the heart. It then activates the production of plasmin, which causes the clots to disintegrate. This unblocks the blood vessel and allows blood flow to resume to the affected organ. Alteplase must be given as soon as possible after the onset of symptoms of a heart attack, pulmonary embolism or ischaemic stroke, to reduce the amount of damage to the affected organ. Treatment for ischaemic stroke must be started within 4.5 hours of onset of the stroke symptoms and only after a type of stroke caused by bleeding in the brain (haemorrhagic stroke) has been ruled out. Alteplase is given by injection or infusion (drip) into a vein to break up the blood clot. You will also be given heparin and aspirin to reduce the risk of further blood clots forming. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction while having treatment with this medicine, inform your doctor or pharmacist immediately. Pregnancy and breastfeedingCertain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine. This medicine should only be used during pregnancy in life threatening circumstances, where the expected benefit is greater than any possible risk to the developing baby. There is a risk of bleeding in both the mother and the baby. If the medicine is given in the first 18 weeks of pregnancy it may possibly lead to premature separation of the placenta. Seek medical advice from your doctor before breastfeeding if you have been given this medicine. Side effectsMedicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people treated with this medicine will experience that or any side effect. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist. How can this medicine affect other medicines?There is an increased risk of bleeding if any of the following medicines are used before, during, or in the 24 hours after treatment with alteplase:Other medicines containing the same active ingredientThere are currently no other medicines available in the UK that contain alteplase as the active ingredient. Last updated 17.10.2012 The materials in this web site are in no way intended to replace the professional medical care, advice, diagnosis or treatment of a doctor. The web site does not have answers to all problems. Answers to specific problems may not apply to everyone. If you notice medical symptoms or feel ill, you should consult your doctor for further information see our Terms and conditions.
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