Aldactide spironolactone What is it used for?How does it work?Aldactide tablets contain two active ingredients; spironolactone, which is a type of medicine called a potassium sparing diuretic and hydroflumethiazide, which is a type of medicine called a thiazide diuretic.
Spironolactone works by blocking the actions of a hormone in the body called aldosterone. This hormone is produced by glands found above the kidneys called the adrenal glands. Aldosterone acts in the kidneys, where it is involved in controlling the balance of salt and water in the body. Blocking the action of aldosterone causes the kidneys to increase the amount of salts such as sodium that they filter out of the blood and into the urine. ADVERTISEMENT CONTINUE READING BELOW Hydroflumethiazide works by directly causing the kidneys to increase the amount of salts such as potassium and sodium that are filtered out of the blood and into the urine. When these salts are filtered out of the blood by the kidneys, water is also drawn alongside. Both these diuretics therefore increase the amount of water that is drawn out of the blood and into the urine. This helps excess fluid to be removed from the body. Removing water from the blood decreases the volume of fluid circulating through the blood vessels. The drop in fluid volume results in a drop in the pressure of the fluid within the blood vessels, which helps to lower high blood pressure. It also decreases the effort required by the heart to pump blood around the body. If used alone, hydroflumethiazide can cause the level of potassium in the blood to drop too low (hypokalaemia). Spironolactone on the other hand prevents potassium loss. It is included in this medicine not only to improve the effectiveness of hydroflumethiazide, but also to prevent excessive potassium loss that this diuretic might otherwise cause. This medicine is used in heart failure, where the pumping mechanism of the heart is less effective. Heart failure can cause fluid to build up in the lungs, causing breathlessness and in the lower limbs, causing swollen ankles. Diuretic medicines are used to remove this excess fluid into the urine. This relieves the symptoms of heart failure and also makes it easier for the heart to pump the blood around the body. For this reason, it is recommended that you take this medicine in the morning. Seek further advice from your doctor or pharmacist. Warning!This medicine may cause fatigue and dizziness. For this reason you should avoid consuming large amounts of foods that have a high potassium content, for example dried fruit, bananas, tomatoes and 'low sodium' salt, while you are taking the medicine. People whose kidneys are not producing urine. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately. Pregnancy and breastfeedingCertain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or oakley jupiter planning a pregnancy, before using any medicine. ADVERTISEMENT CONTINUE READING BELOW This medicine should not be used during pregnancy unless the expected benefit to the mother is greater than the possible risks to the developing baby. It is not recommended for mothers who are breastfeeding. Seek further medical advice from your doctor. Side effectsMedicines and their possible side effects can affect oakely glasses individual people in different ways. The following are some of the side effects which oakley lenses that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist. How can this medicine affect other medicines?It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or okaleys pharmacist before taking any new medicines while taking this one, to make sure that the combination is safe. This medicine is likely to have an additive effect with other medicines that decrease blood pressure, particularly medicines that are used to treat high blood pressure (antihypertensives).
This may cause dizziness, which can usually be relieved by lying down until the symptoms pass. If you feel dizzy while taking this medicine in combination with other medicines that can lower blood pressure you should let your doctor know, as your doses may need adjusting. The following medicines can also raise the level of potassium in the blood and if you take any of these with Aldactide the level of potassium in your blood should be regularly monitored:.
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